Search results for "Classic KS"

Risk of classic Kaposi sarcoma with residential exposure to volcanic and related soils in Sicily

2009

Purpose Before AIDS, endemic (African) Kaposi sarcoma (KS) was noted to occur in volcanic areas and was postulated to result from dirt chronically embedded in the skin of the lower extremities. The primary cause of all KS types is KS-associated herpesvirus (KSHV) infection, but cofactors contribute to the neoplasia. We investigated whether residential exposure to volcanic or related soils was associated with the risk of classic Kaposi sarcoma (cKS) in Sicily. Methods Risk of incident cKS ( N  = 141) compared with population-based KSHV seropositive controls ( N  = 123) was estimated for residential exposure to four types of soil, categorized with maps from the European Soil Database and dire…